|Epic Code:||LAB6333||Epic Name:||Alpha-2-Antiplasmin Activity|
|Synonyms:||Alpha-2-Antiplasmin Activity; Antiplasmin; Anti-Plasmin Functional Assay|
|Methodology:||Chromogenic (synthetic substrate) activity assay|
|Turnaround Time:||Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-8 days.|
|Optimal Volume:||2.7 mL (in 3 mL tube) - filled to fill line on the tube.|
|Minimum Volume:||1.8 mL (in 2 mL tube) - filled to fill line on the tube.|
|Container:||Blue Na Citrate, 3.2% - fill to fill line on tube.|
|Collection Instructions:||See link to Specimen Collection and Processing for Coagulation Specimens.|
|Causes for Rejection:||Underfilled tubes, nonfrozen or hemolyzed specimens.|
Processing and Shipping
|Specimen Processing:||Centrifuge the specimen at 1700 x g for 15 minutes (or at a speed and time required to consistently produce platelet-poor plasma - platelet count less than 10,000/uL). Aliquot within 4 hours of collection 1 mL; 0.5 mL minimum of platelet-poor plasma. Store in freezer.|
|Shipping Instructions:||Ship frozen.|
|Test Performed at or Referral Lab||Lab Sendouts (ARUP)|
|Referral Lab number:||98727|
A reference range has not been established for patients less than 1 day old.
Alpha-2 Antiplasmin is a specific inhibitor of Plasmin. A deficiency may result in a bleeding tendency. Homozygous deficiency may cause severe bleeding. Elevated levels may cause thrombosis.
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