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Alpha-2-Antiplasmin Chromogenic


Sunquest Code:A2AP  
Epic Code:LAB6333Epic Name:Alpha-2-Antiplasmin Activity
Synonyms:Alpha-2-Antiplasmin Activity; Antiplasmin; Anti-Plasmin Functional Assay
Methodology:Chromogenic (synthetic substrate) activity assay
CPT Code:85410
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-8 days.
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Container:Blue Na Citrate, 3.2% - fill to fill line on tube.
Collection Instructions:See link to Specimen Collection and Processing for Coagulation Specimens.
Causes for Rejection:Underfilled tubes, nonfrozen or hemolyzed specimens.


Processing and Shipping

Specimen Processing:Centrifuge the specimen at 1700 x g for 15 minutes (or at a speed and time required to consistently produce platelet-poor plasma - platelet count less than 10,000/uL). Aliquot within 4 hours of collection 1 mL; 0.5 mL minimum of platelet-poor plasma. Store in freezer.
Shipping Instructions:Ship frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:98727


Interpretive

Reference Range:

1-4 d

55-115%

5-29 d

70-130%

30-89 d

76-124%

90-179 d

76-140%

180-364 d

83-139%

1-5 y

93-117%

6 y

89-110%

7-9 y

88-147%

10-11 y

90-144%

12-13 y

87-142%

14-15 y

83-136%

16-17 y

77-134%

18 y and older

82-133%

A reference range has not been established for patients less than 1 day old.

 

Use:

Alpha-2 Antiplasmin is a specific inhibitor of Plasmin. A deficiency may result in a bleeding tendency. Homozygous deficiency may cause severe bleeding. Elevated levels may cause thrombosis.

 

 



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