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Anti-Treponema


Sunquest Code:TREPAB  
Epic Code:LAB3791Epic Name:Treponema Antibody
Synonyms:Anti Treponema; Syphilis, Total Antibody Screen; Treponema Pallidum Antibody
Methodology:Chemiluminescent immunoassay (CLIA)
CPT Code:86780
Turnaround Time:Performed Mon-Fri; results are reported within 2 days.
Associated Links:

Syphilis Serology Algorithm



Collection Instructions

Specimen:Blood
Optimal Volume:2.0 mL
Minimum Volume:0.8 mL (This volume will not permit reflex testing if positive.)
Container:Red or gold (gel). Alternate: Red (no gel).
Causes for Rejection:Hyperlipemic, particulate matter, bacterial contamination and grossly hemolyzed samples.
Contraindications:This test (TREPAB) is not used to test CSF specimens; see VDRL, Cerebrospinal.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator up to 7 days. Alternatively, freeze at 20 C or below.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Infectious Diseases Diagnostic Laboratory-Virology  (UMMC-East Bank)


Interpretive

Reference Range:

Negative

Less than 0.9

Equivocal

0.9-1.09

Positive

Greater than 1.1

 

 

Use:Use for screening for exposure to Treponema pallidum. The Anti-Treponema screening test tends to remain positive for life, and therefore does not distinguish between active and post syphilis infections. All positive and equivocal results will automatically reflex to a non-specific Rapid Plasma Reagin (RPR) test. If the Anti-Treponema is positive, and the RPR is positive, this is presumptive evidence of current infection, inadequately treated infection, persistent infection or reinfection. If the Anti-Treponema is positive and the RPR is negative, then a second Treponema specific test, Treponema pallidum particle agglutination (TP-PA) will be performed to determine whether the anti-Treponema antibody is falsely positive or is detecting early infection. If the latter is suspected, repeat testing in approximately 2 weeks is recommended.


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