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Cyclosporine


Sunquest Code:CYC  
Epic Code:LAB874Epic Name:CYCLOSPORINE
Synonyms:CSA; Cyclosporine A; Gengraf; Sandimmune, Neoral
Methodology:Liquid chromatography/tandem mass spectrometry
CPT Code:80158
Turnaround Time:Performed daily; results are reported the same day.
Special Instructions:Monitor UMMC inpatients Mon, Wed, Fri. Monitor heart and heart-lung transplants on days 2 and 3 post op also. For additional levels, contact the laboratory.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum Volume:0.4 mL
Container:Purple (EDTA). Alternate: Green (lithium heparin, no gel); Green (sodium heparin, no gel).
Collection Instructions:Usual sampling time is immediately prior to next dose.


Processing and Shipping

Specimen Processing:Do not process whole blood. Store in refrigerator.
Shipping Instructions:Ship at room temperature.
Test Performed at or Referral Lab Drug Analysis  (UMMC-East Bank)


Interpretive

Critical Range:Greater than 400 ug/L
Therapeutic Range:

 

ug/L

Kidney Transplant (mo post transplant)

 

Pediatric

 

0-3 mo

175-200

3-6 mo

150-175

6-9 mo

125-150

9-12 mo

100-125

Greater than 12 mo

75-100

Adult

 

0-3 mo

175-200

3-6 mo

150-200

6-12 mo

125-150

Greater than 12 mo

75-100

Heart Transplant (mo post transplant)

 

Pediatric

 

0-12 mo

200-250

Greater than 12 mo

100-125

EBV PCR >1000 copies/mL

80-100

Adult

 

0-3 mo

150-250

3-6 mo

125-225

6-12 mo

100-200

Greater than 12 mo

50-150

Heart/Lung Block

200-250

Lung Transplant

 

0-12 mo

175-225

Greater than 12 mo

125-175

Liver Transplant (mo post transplant)

 

0-6 mo

150-200

Greater than 6 mo

100-150

Pancreas Transplant (mo post transplant)

 

0-6 mo

200-250

6-12 mo

150-200

Greater than 12 mo

100-150

Bone Marrow Transplant

200-400

 

 

Use:Therapeutic drug monitoring and assess toxicity.


Click HERE to Report test errors or omissions.