Oxalate, Urine, Quantitative - Special Handling


Sunquest Code:UOXALA  
Epic Code:LAB3851Epic Name:Oxalate Quantitative Urine
Methodology:Spectrophotometry
CPT Code:83945
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-4 days.
Special Instructions:UMMC-East Bank: Send to Specimen Management for addition of sulfamic acid.
Associated Links:

Urine Collection Procedure



Collection Instructions

Specimen:Urine, 24 hour collection.
Optimal Volume:Submit entire 24 hour collection; analysis requires 1.5 mL
Minimum\Peds Volume:1.5 mL
Container:3 L plastic jug (Plastic leakproof container, sterile)
Collection Instructions:Refrigerate during collection.
Patient Preparation:Since vitamin C (ascorbic acid) quickly degrades to oxalate in non-acidified urine, patients should discontinue use of vitamin C supplements during and for 48 hours prior to urine collection for oxalate.
Causes for Rejection:Room temperature or refrigerated specimens after processing. Aliquots greater than 4 mL per container.


Processing and Shipping

Specimen Processing:Mix collection well and aliquot 4 mL, 1.5 mL minimum into a transfer tube. Add 20 mg sulfamic acid and mix well. Do not exceed 4 mL of urine per aliquot. If sulfamic acid is not available, send frozen unadjusted specimen. Freeze immediately. Store frozen. Separate specimens must be submitted when multiple tests are ordered. Record total volume and collection time entered on transport tube and test request form. This information is required for test interpretation.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:20482


Interpretive

Reference Range:

Age

mg/d

0-12 y

7-31

Male, 13 years and older

16-49

Female, 13 years and older

13-40

 

 

Use:

Formation of the sparingly soluble calcium oxalate salt in the urinary tract is a major factor in urolithiasis. Oxalate in urine may arise either as an end-product of intermediary metabolism or from dietary sources. A decreased excretion of oxalate in the urine is associated with hyperglycinemia and hyperglycinuria. An increased excretion of oxalate can be attributed to increases in ingestion of oxalate precursors or oxalate-rich foods, formation of oxalate due to metabolic defects such as in primary hyperoxaluria, and oxalate absorption in a number of patients with bowel disease, ileal resection, biliary diversion, pancreatic insufficiency, sprue, small intestinal stasis and bacterial overgrowth and following jejunoileal bypass or bowel resection for the treatment of obesity.

 



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