Selenium, Serum or Plasma

Sunquest Code:SEL  
Epic Code:LAB579Epic Name:Selenium
Methodology:Inductively coupled plasma/mass spectrometry
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported in 1-2 days.

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Collection Instructions

Optimal Volume:4 mL
Minimum\Peds Volume:1.2 mL
Container:Trace Element, EDTA (DE) (Trace Element, Serum (DB))
Patient Preparation:Diet, medication and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician).
Causes for Rejection:Separator tubes. Specmens that are not separated from the red cells or clot within 2 hours. Specimens collected in containers other than specified. Specimens transported in containers other than specified.

Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aliquot 2 mL, 0.5 mL minimum into a metal-free plastic vial. Store at room temperature. Also acceptable refrigerated or frozen.
Shipping Instructions:Ship at room temperature. Also acceptable refrigerated or frozen.
Stability:Indefinitely at room tempearture, refrigerated or frozen. If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:25023


Reference Range:23-190 ug/L
Serum selenium levels can be used in the determination of deficiency or toxicity. Plasma and serum contains 75 percent of the selenium measured in whole blood and reflects recent dietary intake. Selenium deficiency can occur endemically or as a result of sustained TPN or restricted diets and has been associated with cardiomyopathy and may exacerbate hypothyroidism. Selenium toxicity is relatively rare. Excess intake of selenium can result in symptoms consistent with selenosis and include gastrointestinal upset, hair loss, white blotchy nails and mild nerve damage.  

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