C1 Esterase Inhibitor


Sunquest Code:C1INH  
Epic Code:LAB3345Epic Name:C1 Esterase Inhibitor Total
Synonyms:Complement 1 Esterase Inhibitor, Quantitation
Methodology:Nephelometry
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.0 mL
Container:Red or gold (gel) (Red (no gel))


Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.4 mL minimum. Freeze within 2 hours. Separate specimens must be submitted when multiple tests are ordered.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50140


Interpretive

Reference Range:21-39 mg/dL
Use:A deficiency of functionally active component of C1-INH may lead to life-threatening angioedema. Two major forms of C1-INH deficiency have been reported: the congenital form and the acquired form. In the congenital form, termed hereditary angioedema (HAE), there is a quantitative deficiency in C-1-esterase inhibitor.


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