Carcinoembryonic Antigen


Sunquest Code:CEA  
Epic Code:LAB57Epic Name:CEA
Synonyms:CEA
Methodology:Chemiluminescent immunoassay
Turnaround Time:Performed and reported 24 hours/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:1.4 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Serum not separated from cells within 8 hours after collection. Gross hemolysis.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.6 mL minimum. Store in refrigerator or freeze.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Stability:Stability: Room temperature - 8 hours; refrigerated - 48 hours; frozen - indefinitely.
Test Performed at or Referral Lab Chemistry  (UMMC-East Bank)


Interpretive

Reference Range:Nonsmokers: 0-2.5 ug/L; Smokers: 0-5.0 ug/L The ADVIA Centaur CEA method is used. Results obtained with different assay methods or kits cannot be used interchangeably.
Use:Monitoring of patients with carcinoma of the colon, pancreas and breast neoplasm. At least two progressive elevations of CEA at one month intervals may herald tumor recurrence 3-36 months before clinical evidence of metastasis. A shallow rise may signal local recurrence, while a large rise in values may indicate hepatic metastasis. CEA levels are increased in smokers.


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