Fungal Antibodies by CF with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion


Sunquest Code:FUNGAR  
Epic Code:LAB8010Epic Name:Fungal Antibodies
Synonyms:Fungus; Fungal Antibodies by CF
Methodology:Complement fixation, enzyme-linked immunosorbent assay, immunodiffusion.
CPT Code:86606, 86612, 86635, 86698 x2, 86612
Test Includes:Aspergillus Antibody, Coccidiodes Antibody, Histoplasma Mycelia Antibody, Histoplasma Yeast Antibody by CF. Blastomyces Antibody by EIA with reflex to immunodiffusion.
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 2-6 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent. Convalescent specimens must be received within 30 days from receipt of the acute specimens.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Hemolyzed, icteric or lipemic specimens.


Processing and Shipping

Specimen Processing:Separate serum from cells within 2 hours of collection. Centrifuge and aliquot 1 mL, 0.4 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3000235


Interpretive

Reference Range:
Aspergilus Ab Less than 1:8 titer
Coccidiodes Ab Less than 1:2 titer
Histoplasma Mycelia By report
Histoplasma Yeast By report
Blastomyces dermatitidis Antibodies by EIA 0.9 IV or less: Negative
1.0-1.4 IV: Equivocal
1.5 IV or greater: Positive
Blastomyces dermatitidis Antibodies by Immunodiffusion None detected
Negative fungal serology does not rule out the possibility of current infection. If Blastomyces antibodies are equivocal or positive by EIA, then Blastomyces Immunodiffusion will be added.


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