Porphobilinogen (PBG) Deaminase, RBC


Sunquest Code:PORDEA  
Epic Code:LAB6890Epic Name:Porphobilinogen Deaminase RBC
Synonyms:Erythrocyte Porphobilinogen (PBG) Deaminase
Methodology:Enzymatic fluorometry
CPT Code:82657
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-6 days.
Special Instructions:Automated hemoglobin result must be included with specimen.


Collection Instructions

Specimen:Whole blood
Optimal Volume:3 mL
Minimum\Peds Volume:1 mL
Collection Instructions:Perform automated hemoglobin on EDTA whole blood before preparing for transport.


Processing and Shipping

Specimen Processing:Do not centrifuge. Aliquot 3 mL, 1 mL minimum to an ARUP transport tube. Indicate specimen hemoglobin on container. Store whole blood frozen.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:99550


Interpretive

Reference Range:2.10-4.30 mU/g Hb
Use:Porphobilinogen (PBG) deaminase (hydroxymethylbilane synthase or uroporphyrinogen I synthase) is expressed in units of mU per gram hemoglobin at 37 degrees C. In persons genetically susceptible to acute intermittent porphyria (AIP), PBG deaminase concentrations are approximately half of reference values. Normal concentrations of erythrocyte PBG deaminase may include abnormal forms of hepatic PBG deaminase.


Click HERE to Report test errors or omissions.
*If no email program is associated with this computer, please contact:
systemlabguide@fairview.org for TestID: 1316"