PTT 1:2 Mix


Sunquest Code:PTT1T2  
Epic Code:LAB3701Epic Name:PTT Mixing Studies
Synonyms:Partial Thromboplastin Time 1:2 Mix; PTT Mix
Methodology:APTT assay of patient/normal plasma mixture at l:2 dilution
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Turnaround time is 1-2 hour if received during lab hours (see Associated Link).
Special Instructions:A thrombin time will be performed. If thrombin time is greater than 19.0 seconds and the PTT-LA is greater than 45 seconds, a hepzyme will be performed (for an additional charge).
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:Two to three 3 mL tubes, each containing 2.7 mL blood; each filled to fill line on the tube.
Minimum\Peds Volume:One 3 mL tube containing 2.7 mL blood; filled to fill line on the tube.
Collection Instructions:See link to Specimen Collection and Processing for Coagulation Specimens.
Causes for Rejection:Underfilled tubes or clotted specimens.


Processing and Shipping

Specimen Processing:See link to Specimen Collection and Processing for Coagulation Specimens.
Shipping Instructions:See link to Specimen Collection and Processing for Coagulation Specimens.
Test Performed at or Referral Lab Special Coagulation  (UMMC-East Bank)


Interpretive

Reference Range:

1 year and older

Patient

31-45 seconds

1:2 Mix

31-45 seconds

Age specific reference ranges have not been established for the PTT in children less than 6 months of age. The PTT may be expected to be higher in neonates than in adults.

 

Use:If the PTT 1:2 Mix corrects to normal, this suggests a factor deficiency present. If it does not correct to normal, a Lupus Battery (lupus anticoagulant test) is recommended. If that is negative, there could be a factor inhibitor present.


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