Fibrinogen Antigen


Sunquest Code:FIBAG  
Epic Code:LAB6052Epic Name:Fibrinogen Antigen
Synonyms:Factor 1 Antigen
Methodology:Radial immunodiffusion
CPT Code:85385
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 2-4 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Causes for Rejection:Underfilled tube, hemolyzed specimens


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 1 mL minimum. Store in freezer.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:30135 (FIBAG)


Interpretive

Reference Range:149-353 mg/dL
Use:Fibrinogen abnormalities can be either quantitative (hypofibrinogenemia), qualitative (dysfibrinogenemia) or both. Patients can exhibit bleeding tendencies (25% of cases), pregnancy loss, thrombotic complications (20% of cases), difficulties in wound healing, or no symptoms (53% of cases). The fibrinogen antigen will detect the quantity of the molecule only. The Clauss Fibrinogen assay will detect the level of fibrinogen activity. A discrepancy between the two tests is indicative of dysfibrinogenemia. Therefore, the Fibrinogen Antigen is usually assayed if the Clauss Fibrinogen is low.


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