Clomipramine and Desmethylclomipramine


Sunquest Code:CLOMI  
Epic Code:LAB3385Epic Name:Clomipramine and Desmethylclomipramine
Synonyms:Anafranil
Methodology:Liquid chromatography/Tandem mass spectrometry
Test Includes:Clomipramine and desmethylclomipramine (norclomipramine).
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.


Collection Instructions

Specimen:Blood
Optimal Volume:4 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:With patient at steady-state, collect sample immediately prior to next dose (trough).


Processing and Shipping

Specimen Processing:Centrifuge and transfer serum/plasma with a plastic pipet. Aliquot 2 mL, 0.5 mL minimum. Store at room temperature.
Shipping Instructions:Ship at room temperature.
Stability:Up to 3 days at room temperature; for longer storage, refrigerate or freeze.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:890


Interpretive

Reference Range:Clomipramine and Desmethylclomipramine, Total: 230-450 ng/mL
Use:Therapeutic drug monitoring and assess toxicity.


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