Doxepin and Desmethydoxepin

Sunquest Code:DOXEP  
Epic Code:LAB3434Epic Name:Doxepin and Desmethydoxepin
Synonyms:Adapin; Sinequan
Methodology:Liquid chromatography/Tandem mass spectrometry
CPT Code:80335
Test Includes:Doxepin and its metabolite N-desmethyldoxepin (nordoxepin)
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.

Collection Instructions

Optimal Volume:4 mL
Minimum\Peds Volume:0.6 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:With patient at steady-state level, collect sample immediately prior to next dose (trough).

Processing and Shipping

Specimen Processing:Centrifuge and transfer serum/plasma with a plastic pipet. Aliquot 2 mL, 0.24 mL. Store at room temperature up to 3 days, alternatively refrigerate or freeze..
Shipping Instructions:Ship at room temperature up to 3 days.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:45


Critical Range:500 ng/mL
Reference Range:Doxepin and metabolite: 50-150 ng/mL
Use:Monitor therapeutic drug levels and assess toxicity.

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