Phenobarbital Level


Sunquest Code:PHENO  
Epic Code:LAB30Epic Name:Phenobarbital Level
Synonyms:Also see Free Phenobarbital (FPHENO, LAB3482)
Methodology:Turbidimetric rate
CPT Code:80184
Turnaround Time:Performed and reported 24 h/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.8 mL
Collection Instructions:Trough level is preferred; collect immediately before dose. It is advisable to monitor at the same time in the dosing schedule.
Causes for Rejection:Collection in a gel tube.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.3 mL minimum. Store in room temperature up to 48 hours. Alternatively, refrigerate.
Shipping Instructions:Ship at room temperature to arrive within 48 hours. Alternatively, ship at refrigerated temperature.
Test Performed at or Referral Lab Chemistry  (Fairview Range - FRMC, UMMC-West Bank, UMMC-East Bank, Fairview Southdale - FSH)


Interpretive

Critical Range:Greater than 50 mg/L
Therapeutic Range:15-40 mg/L
Use:Monitor therapeutic drug level of phenobarbital; use with primidone levels to monitor therapeutic drug level of primidone; evaluate phenobarbital toxicity. Half-life is 50-120 h (adult); and 40-70 h (child).


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