Loxapine and 8-Hyroxyloxapine


Sunquest Code:LOXAP  
Epic Code:LAB3120Epic Name:Loxapine and 8 Hyroxyloxapine
Synonyms:Loxitane; 8 Hydroxyloxapine
Methodology:Gas chromatography/Tandem mass spectrometry
CPT Code:80342
Test Includes:Loxapine and 8-hydroxyloxapine.
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.


Collection Instructions

Specimen:Blood
Optimal Volume:4 mL
Minimum\Peds Volume:1.4 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:Usual sampling time is immediately prior to next dose (trough).


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 0.6 mL minimum. Store at room temperature.
Shipping Instructions:Ship at room temperature.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:65


Interpretive

Critical Range:Loxapine: Greater than 60.0 ng/mL; 8-Hydroxyloxapine: Greater than 200.0 ng/mL
Reference Range:Loxapine: 5-30 ng/mL; 8-hydroxyloxapine:.20.0-100.0 ng/mL
Limitations:Therapeutic range has not been established.
Use:Therapeutic monitoring and assess toxicity.


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