Procainamide & N-Acetylprocainamide (NAPA)


Sunquest Code:PCAIN  
Epic Code:LAB5974Epic Name:Procainamide and NAPA
Synonyms:Pronestyl; N-Acetylprocainamide (NAPA); Proscan-Sr
Methodology:Immunoassay
CPT Code:80192
Test Includes:Procainamide and N-acetyl procainamide (NAPA)
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 1-3 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:Trough level is preferred; collect immediately before dose, but no sooner than 2 hours before. Optimal collection time for peak level is 1-2 hours after oral dose. Optimal collection time for I.V. dose: immediately after loading dose and 2 hours, 6-12 hours, and 24 hours after maintenance infusion. Optimal sampling for oral dose: three steady-state samples over one oral dosing interval (i.e., immediately prior to dose and two more samples at equally spaced intervals).
Causes for Rejection:Gel-barrier tube; severely hemolyzed, lipemic or icteric speicmen.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (LabCorp via MedTox)
Referral Lab number:990123


Interpretive

Reference Range:

 

ug/mL

Procainamide

4.0-10.0

NAPA

10.0-30.0

 

 

 

Use:Monitor therapeutic dosing and evaluate toxicity. Half-life is 2-4 h (procainamide); 8 h (NAPA).


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