Islet Cell Antibody, IgG
| Sunquest Code: | ISAB | ||
| Epic Code: | LAB3573 | Epic Name: | Islet Cell Antibody IgG |
| Synonyms: | Pancreatic Islet Cell Antibody | ||
| Methodology: | Indirect fluorescent antibody | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-3 days. | ||
| Compliance: | Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.5 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Plasma; grossly hemolyzed or lipemic |
Processing and Shipping
| Specimen Processing: | Separate serum from cells within 2 hours of collection. Centrifuge and aliquot 1 mL, 0.15 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | Stability: Room temperature - 48 hours; refrigerated - 2 weeks; frozen - 1 year. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50138 (ANTI-ISLET) |
Interpretive
| Reference Range: | Less than 1:4 titer (no antibody detected) Islet cell antibodies (ICAs) are associated with type 1 diabetes (T1D), an autoimmune endocrine disorder. These antibodies may be present in individuals years before the onset of clinical symptoms. |
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