Islet Cell Antibody, IgG
| Sunquest Code: | ISAB | ||
| Epic Code: | LAB3573 | Epic Name: | Islet Cell Antibody IgG |
| Synonyms: | Pancreatic Islet Cell Antibody | ||
| Methodology: | Indirect fluorescent antibody | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-3 days. | ||
| Compliance: | This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.5 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Plasma; grossly hemolyzed or lipemic |
Processing and Shipping
| Specimen Processing: | Separate serum from cells within 2 hours of collection. Centrifuge and aliquot 1 mL, 0.15 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | Stability: Room temperature - 48 hours; refrigerated - 2 weeks; frozen - 1 year. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50138 (ANTI-ISLET) |
Interpretive
| Reference Range: | Less than 1:4 titer (no antibody detected) Islet cell antibodies (ICAs) are associated with type 1 diabetes (T1D), an autoimmune endocrine disorder. These antibodies may be present in individuals years before the onset of clinical symptoms. |
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