Sunquest Code:HCY  
Epic Code:LAB3520Epic Name:Homocysteine
Synonyms:Homocysteine, Total; Homocystine; HCY
Methodology:Chemiluminescent immunoassay
Turnaround Time:Performed once/week; results are reported the next day.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1 mL
Container:Purple (EDTA) on ICE (Green (sodium heparin, no gel) on ICE)
Causes for Rejection:Not collected on ice; gross hemolysis. Sample not separated from cells within 2 hours of collection.

Processing and Shipping

Specimen Processing:Within 2 hours, centrifuge and aliquot 1 mL, 0.4 mL minimum.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Stability: Plasma/serum is stable refrigerated for up to 14 days.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Reference Range:4-12 umol/L
Use:Diagnosis of homocystinuria and monitoring levels for patient management. Moderately elevated levels of homocysteine in the plasma could be due to heterozygosity of cystathionine beta-synthase (CBS) gene defect, defects in the remethylation pathway, other genetic factors, nutritional, or non-specific cause, such as renal failure.

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