Bupropion


Sunquest Code:BUROP  
Epic Code:LAB3341Epic Name:Bupropion Level
Synonyms:Wellbutrin; Zyban
Methodology:Liquidchromatography/Tandem mass spectrometry
CPT Code:80338
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.
Special Instructions:Sample must be aliquoted into a bupropion analysis tube after centrifuging. See Associated Link.
Compliance:

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.



Collection Instructions

Specimen:Blood
Optimal Volume:6 mL
Minimum\Peds Volume:2.6 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:Usual sampling time is immediately prior to next dose (trough). Deliver to laboratory immediately.
Causes for Rejection:Gel top tubes; non frozen samples. Samples not aliquoted into a bupropion analysis tube.


Processing and Shipping

Specimen Processing:Centrifuge wiithin 30 minutes of collection. Aliquot 3 mL, 1.2 mL minimum into a MedTox aliquot tube for buprioprion analysis containing sodium citrate monobasic (white powder). Do not use standard aliquot tubes. See Associated Link. Freeze immediately.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:178


Interpretive

Reference Range:Bupropion: 50-100 ng/mL; Hydroxybupropion: 600-2000 ng/mL


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