Sunquest Code:BUROP  
Epic Code:LAB3341Epic Name:Bupropion Level
Synonyms:Wellbutrin; Zyban
Methodology:Liquidchromatography/Tandem mass spectrometry
CPT Code:80338
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.
Special Instructions:Sample must be aliquoted into a bupropion analysis tube after centrifuging. See Associated Link.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Collection Instructions

Optimal Volume:6 mL
Minimum\Peds Volume:2.6 mL
Container:Red (no gel) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:Usual sampling time is immediately prior to next dose (trough). Deliver to laboratory immediately.
Causes for Rejection:Gel top tubes; non frozen samples. Samples not aliquoted into a bupropion analysis tube.

Processing and Shipping

Specimen Processing:Centrifuge wiithin 30 minutes of collection. Aliquot 3 mL, 1.2 mL minimum into a MedTox aliquot tube for buprioprion analysis containing sodium citrate monobasic (white powder). Do not use standard aliquot tubes. See Associated Link. Freeze immediately.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:178


Reference Range:Bupropion: 50-100 ng/mL; Hydroxybupropion: 600-2000 ng/mL

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