Alpha Fetoprotein, Amniotic Fluid with Reflex to Acetylcholinesterase and Fetal Hemoglobin


Sunquest Code:AFPACE  
Epic Code:LAB6894Epic Name:Amniotic Reflex to Acetylchol
Synonyms:AFP, Amniotic Fluid
Methodology:Chemiluminescense/Electrophoresis
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 3-4 days, 3-11 days if reflex testing is required.
Special Instructions:Include gestational age at time of collection or estimated due date on the test request form. See Associated Links.
Associated Links:

Patient History for Prenatal Cytogenetics



Collection Instructions

Specimen:Amniotic Fluid
Optimal Volume:2.5 mL
Minimum\Peds Volume:1.5 mL
Container:Plastic leakproof container, sterile
Causes for Rejection:Specimens contaminated with fetal blood


Processing and Shipping

Specimen Processing:Store at room temperature.If ordered with CSNPMF (Cytogenomic SNP Microarray Fetal), a single tube can be sent to ARUP for testing of both tests. If ordered alone, send AFP to Cytogenetics for processing prior to sending to ARUP.
Shipping Instructions:Ship at room temperature. Protect from extreme temperatures.
Stability:Stability: 2 weeks at room temperature; 4 months refrigerated; 3 years frozen
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3000142


Interpretive

Reference Range:
AFP, Amniotic Fluid By report. Ranges are based upon the weeks of gestation.
Acetylcholinesterase, Amniotic Fluid Negative
Fetal Hemolgobin, Amniotic Fluid Negative
Multiple of Median 1.99 or less
   
Use:Elevated AFAFP levels are associated with open fetal defects such as spina bifida, anencephaly, gastroschisis and omphalocele.


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