ENA Antibody Panel


Sunquest Code:ENAABY  
Epic Code:LAB3450Epic Name:ENA Antibody Panel
Synonyms:ENA Panel; Extractable Nuclear Antigen, Antibodies, Panel
Methodology:Multiplex bead assay
CPT Code:86235, 86235, 86235, 86235, 86235
Test Includes:Scleroderma antibody, Smith antibody, RNP antibody, SSA antibody and SSB antibody.
Turnaround Time:Performed Mon-Fri; results are reported the same day.
Special Instructions:When possible, order specific individual antibodies if entire panel is not needed.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Gross hemolysis


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Interpretive

Reference Range:

Component

Reference Interval

RNP (U1) (Ribonucleic Protein)(ENA) Antibody IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

Smith (ENA) Antibody, IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

SSA (Ro) (ENA) Antibody, IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

SSB (La) (ENA) Antibody IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

Scleroderma (Scl-70)(ENA) Antibody, IgG

Negative: Less than 1.0 AI

Equivocal: 0.9-1.0 AI

Positive: 1.0 AI or greater

 

Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.

 



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