Anti-Neutrophil Cytoplasmic Antibody (ANCA), IgG by IFA with Reflex to Titer


Sunquest Code:ANCAF  
Epic Code:LAB8038Epic Name:ANCA IGG by IFA with Reflex to Titer
Synonyms:Granulomatosis and Polyangiitis; pANCA; cANCA; ANCAB
Methodology:Indirect fluorescent antibody
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Performed Mon-Fri; results are reported within 2 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Severely lipemic; hemolyzed; plasma, CSF, urine, and other body fluids.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Endocrine  (UMMC-East Bank)


Interpretive

Reference Range:
    Less than 1:10
Use:Anti-Neutrophil Cytoplasmic Antibodies (C-ANCA = granular cytoplasmic staining; P-ANCA = perinuclear staining) are found in the serum of over 90% of patients with certain necrotizing systemic vasculitides, and usually in less than 5% of patients with collagen vascular disease or arthritis.


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