SSB (La) (ENA) Antibody, IgG

Sunquest Code:SSBIGG  
Epic Code:LAB6341Epic Name:SSB La ENA Antibody IgG
Synonyms:Sjogren's La Antibody; La Antibody; Extractable Nuclear Antigen Antibody
Methodology:Multiplex flow immunoassay
Turnaround Time:Performed Mon-Fri; results reported the same day.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Gross hemolysis or severely lipemic specimens.

Processing and Shipping

Specimen Processing:Centrifuge ASAP and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Reference Range:


Less than 1.0 AI


1.0 AI or greater


Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.


Use:SSB (La) antibody is seen in 50-60% of Sjogren's syndrome cases and is specific if it is the only ENA antibody present. 15-25% of patients with SLE and 5-10% of patients with progressive systemic sclerosis (PSS) also have this antibody.

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