Sirolimus


Sunquest Code:RAPA  
Epic Code:LAB875Epic Name:Sirolimus Level
Order Instructions:Comment last dose information. Do not cancel this test if the specimen is frozen, comment "Specimen frozen" when test requesting.
Synonyms:Rapamune; Rapamycin
Methodology:Liquid chromatography/tandem mass spectrometry
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Performed daily; results are reported the same day. Samples will be reported the same day if received by 9:30 am.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.4 mL
Collection Instructions:Usual sampling time is immediately prior to next dose, but no sooner than 2 hours before.
Causes for Rejection:Clotted specimen.


Processing and Shipping

Specimen Processing:Do not process whole blood. Store in refrigerator.
Shipping Instructions:Ship at room temperature.
Test Performed at or Referral Lab Drug Analysis  (UMMC-East Bank)


Interpretive

Critical Range:Greater than 20 ug/L
Therapeutic Range:

 

ug/L

Kidney Transplant

Adult

6-12 mo

Greater than 12 mo

Greater than 5 y

 

 

8-10

5-8

4-6

Heart Transplant

4-10

Lung Transplant

5-15

Hematopoietic Stem Cell

3-12

Pediatric BMT

3-12

 

 

Use:Therapeutic drug monitoring and to assess toxicity.


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