Felbamate Level


Sunquest Code:FELBAM  
Epic Code:LAB7013Epic Name:Felbamate Level
Synonyms:Felbatol
Methodology:Liquid chromatography/Tandem mass spectrometry
CPT Code:80299
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 2-4 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel) (Green (sodium heparin, no gel), Gray (sodium fluoride + potassium oxalate), Purple (EDTA))
Collection Instructions:Trough level preferred.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.5 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Stability after separation fro cells is 48 hours at room temperature; 1 month refrigerated; 6 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:94030


Interpretive

Reference Range:Toxic Range: Greater than 200 ug/mL Therapeutic Range: Not well established The proposed therapeutic range for seizure control is 30-60 ug/mL. Pharmacokinetics vary widely, particularly with co-medications, age and/or compromised renal function. Felbamate use is associated with an increased incidence of liver failure and aplastic anemia.
Use:Optimize drug therapy and monitor patient adherence.


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