Borrelia burgdorferi Antibodies, Total by ELISA (CSF)


Sunquest Code:CLYG  
Epic Code:LAB3390Epic Name:B Burgdorferi Aby CSF
Synonyms:Lyme Antibody Detection
Methodology:Enzyme-linked immunosorbent assay; immunoblot
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-3 days.
Compliance:

The manufacturer has not determined the efficacy of this test when performed on CSF specimens. The performance characteristics of this test were determined by ARUP Laboratories.



Collection Instructions

Specimen:CSF
Optimal Volume:3 mL
Minimum\Peds Volume:0.5 mL
Causes for Rejection:Hemolyzed, contaminated or heat-inactivated specimen


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 3 mL, 0.5 mL minimum. Store refrigerated.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:99483


Interpretive

Reference Range:

0.99 LIV or less

Negative. Antibody to Borrelia burgdorferi not detected

1.00-1.20 LIV

Equivocal. Repeat testing in 10-14 days may be helpful

1.21 LIV or greater

Positive. Probable presence of antibody to Borrelia burgdorferi detected

Once the test is performed; if negative, no further testing is done. If positive or equivocal, immunoblot testing will be performed on the original sample upon receiving a request. Sample will be held for 30 days only.

 

 

Use:

Current CDC recommendations for the serologic diagnosis of Lyme Disease are to screen with a polyvalent EIA test and confirm equivocal and positive results with immunoblot.. Both IgM and IgG immunoblots should be performed on samples less than 4 weeks after appearance of erythema migrans. Only IgG immunoblot should be performed on samples greater than 4 weeks after the disease onset. IgM immunoblot in the chronic stage is not recommended and does not aid in the diagnosis of neuroborreliosis or chronic Lyme disease. Please submit requests for appropriate immunoblot testing within 10 days.

 



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