Porphyrins, Fractionation and Quantitation, Urine

Sunquest Code:PORPU  
Epic Code:LAB6057Epic Name:Porphyrins, Quantitative Urine
Synonyms:Uroporphyrins, Urine; Porphyrins, Total Urinary
Methodology:High performance liquid chromatography
CPT Code:84120
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-4 days.
Special Instructions:Total volume and collection time interval is required. Protect specimen fro light during collection, processing and shipping.

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

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Urine Collection Procedure

Collection Instructions

Specimen:Urine, random or timed collection, protected from light
Optimal Volume:Submit entire collection; analysis requires 2 mL
Container:Plastic leakproof container, sterile (3 L plastic jug)
Collection Instructions:24 hour collection preferred. Protect sample from light.
Causes for Rejection:Not protected from light; stored at room temperature. Body fluids other than urine.

Processing and Shipping

Specimen Processing:Aliquot 4 mL, 2 mL minimum. Protect from light. Store in freezer. Record total volume and collection time interval on transport tube.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2002058


Reference Range:


┬Ámol/mol crt



Heptacarboxylate Porphyrin


Coproporphyrin I


Coproporphyrin III




Use:Urine prophyrins are useful for the evaluation of cutaneous photosensitivity to exclude porphyria cutanea tarda (PCT). Evaluation of neurologic and/or psychiatric symptoms associated with acute porphyrias such as acute intermittent porphyria (AIP) requires urine porphobilinogen (PBG) testing.

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