Zinc Protoporphyrin, Whole Blood Industrial


Sunquest Code:ZPPO  
Epic Code:LAB3233Epic Name:Zinc Protoporphyrin Occupational
Methodology:Hematofluorometry
CPT Code:84202
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.
Special Instructions:Specimen should be tested for lead first to avoid potential contamination problems.


Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.2 mL
Container:Trace Element, EDTA (DE) (Purple (EDTA))
Causes for Rejection:Frozen, hemolyzed or clotted specimen.


Processing and Shipping

Specimen Processing:Aliquot 1 mL, 0.2 mL minimum whole blood. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:20614 (ZPP IND)


Interpretive

Reference Range:

Zinc Protoporphyrin (ZPP), Whole Blood

0-40 µg/dL

Zinc Protoporphyrin (ZPP), to Heme Ratio

0-69 µmol ZPP/mol heme

For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.

 

 

Use: Elevated ZPP results are seen in both early and late iron deficiency, the anemia of chronic disease erythropoietic protoporphyria, and chronic lead poisoning. Causes for false elevations include markedly elevated bilirubin or riboflavin, and hemolyzed, clotted or improperly aliquoted specimens.


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