Mycophenolic Acid and Mycophenolic Acid Glucuronide


Sunquest Code:MYPA  
Epic Code:LAB3628Epic Name:Mycophenolic Acid
Synonyms:Cellcept; Mofetil; Myfortic; MMF; MPA; MPAG
Methodology:Liquid chromatography/tandem mass spectrometry
CPT Code:80180
Test Includes:Mycophenolic acid (MPA) and mycophenolic acid glucuronide (MPAG)
Turnaround Time:Performed twice/week; results are reported the next day.


Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:1 mL
Collection Instructions:Usual sampling time is immediately prior to next dose.
Causes for Rejection:Sample not separated from cells within 2 hours of collection.


Processing and Shipping

Specimen Processing:Within 2 hours, centrifuge and aliquot 1 mL, 0.4 mL minimum. Store in freezer. Whole blood or plasma samples are stable for 4 hours at room temperature, or for 8 hours if refrigerated. Comment last dose information.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Drug Analysis  (UMMC-East Bank)


Interpretive

Critical Range:Greater than 10.00 mg/L MPA
Therapeutic Range:MPA: 1.00-3.50 mg/L, MPAG 30.0-95.0 mg/L
Use:Therapeutic drug monitoring and to assess toxicity.


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