Soluble Transferrin Receptor


Sunquest Code:STR  
Epic Code:LAB3753Epic Name:SOLUBLE TRANSFERRIN RECEPTOR
Synonyms:Transferrin Receptor Level
Methodology:Immunoturbidimetric
CPT Code:84238
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 24 hours.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Green (lithium heparin, no gel), Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Severely hemolyzed, lipemic, icteric.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.3 mL minimum ASAP. Samples are stable refrigerated for 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:70283 (STR)


Interpretive

Reference Range:

Male – 18 y & older

2.2-5.0 mg/L

Female – 18 y & older

1.9-4.4 mg/L

People of African descent and those residing at 5,200 feet (1,600 meters) above sea level were found to have a 6% higher normal value. These differences were additive. No reference values have been established for pregnant females, subjects under 18 years of age, and recent or frequent blood donors.

 

Use:

Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states. In general, to increase sensitivity and specificity, the measurement of serum soluble transferrin receptor should be performed in combination with other tests of iron status, including ferritin, TIBC and serum iron. Refer to table below:

 

 

Test for Changes in:

Iron Deficiency Anemia

Anemia of Chronic Disease

Iron Deficiency & Anemia of Chronic Disease

Ferritin

Iron Sores

Low

High

Normal or High

TIBC

Iron Status

High

Low

Normal or High

Serum Iron

Iron Status

Low

Low

Low

sTfR

Iron Status

High

Normal

High

 

 



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