Thiopurine Metabolites by LC-MS/MS


Sunquest Code:THIOMT  
Epic Code:LAB7078Epic Name:Thiopurine Metabolites by LC-MS/MS
Synonyms:6 Thioguanine; 6 Methylmercaptopurine; Thiopurine Level
Methodology:Liquid chromatography/Tandem mass spectrometry
CPT Code:----------CPTCODES HERE----------
Test Includes:6-TGN and 6-MMPN levels
Turnaround Time:Specimens are sent to reference laboratory Wed-Sun only; results are reported within 3-7 days.


Collection Instructions

Specimen:Whole Blood
Optimal Volume:5 mL
Minimum\Peds Volume:2.5 mL
Patient Preparation:Trough collection (within 1 hour prior to the next dose).
Causes for Rejection:Frozen or hemolyzed samples


Processing and Shipping

Specimen Processing:Do not process. Whole blood. Store in refrigerator. Do not freeze.
Shipping Instructions:Ship at refrigerated temperature Sun-Wed only.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2014484


Interpretive

Reference Range:
By report.    
Use:
Optimize therapy for thiopurine drugs. Identify thiopurine metabolite concentrations that may lead to toxicity.  


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