Thiopurine Metabolites by LC-MS/MS

Sunquest Code:THIOMT  
Epic Code:LAB7078Epic Name:Thiopurine Metabolites by LC-MS/MS
Synonyms:6 Thioguanine; 6 Methylmercaptopurine; Thiopurine Level
Methodology:Liquid chromatography/Tandem mass spectrometry
Test Includes:6-TGN and 6-MMPN levels
Turnaround Time:Results are reported within 3-7 days.

Collection Instructions

Specimen:Whole Blood
Optimal Volume:5 mL
Minimum\Peds Volume:2.5 mL
Container:Purple (EDTA)
Collection Instructions:Collect Mon-Wed noon to ensure specimen integrity and rapid turnaround.
Patient Preparation:Trough collection (within 1 hour prior to the next dose).
Causes for Rejection:Frozen or hemolyzed samples

Processing and Shipping

Specimen Processing:Do not process. Whole blood. Store in refrigerator. Do not freeze.
Shipping Instructions:Ship at refrigerated temperature Sun-Wed only.
Stability:24 hours at room temperature; 5 days refrigerated.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2014484


Reference Range:
By report.    
Optimize therapy for thiopurine drugs. Identify thiopurine metabolite concentrations that may lead to toxicity.  

Click HERE to Report test errors or omissions.
*If no email program is associated with this computer, please contact: for TestID: 3804"