Lysozyme, Serum


Sunquest Code:LYSO  
Epic Code:LAB4190Epic Name:Lysozyme Serum
Methodology:Enzyme-linked immunosorbent assay
CPT Code:85549
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-5 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL blood
Minimum\Peds Volume:1.0 mL blood
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Urine or other body fluids. Hemolyzed, lipemic, icteric or contaminated specimens.


Processing and Shipping

Specimen Processing:Separate serum from cells within 2 hours of collection. Aliquot 1 mL, 0.4 mL minimum, serum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2012039


Interpretive

Reference Range:9-17 ug/mL
Use:Serum and urine lysozyme levels may be elevated in acute myelomonocytic leukemia (FAB-M4), chronic myelomonocytic leukemia (CMML), and chronic myelocytic leukemia (CML). Increased serum lysozyme activity is present in tuberculosis, sarcoidosis, megaloblastic anemias, acute bacterial infections, ulcerative colitis, regional enteritis,and Crohn disease. Elevated levels of urine and serum lysozyme occur during severe renal insufficiency, renal transplant rejection, urinary tract infections, pyleonephritis, glomerulonephritis and nephrosis.


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