Tzanck Smear for HSV

Sunquest Code:NGNCTCoPath Code:NGYN
Epic Code:LAB4600Epic Name:Cytology Non Gyn
Sunquest Code (non-Epic sites):COPATH  
Synonyms:Herpes Cytology
Methodology:Papanicolau stain
Turnaround Time:Performed daily, 0800-1500; result reported within 1-3 days.

Collection Instructions

Specimen:Direct smear from open lesion
Container:Microscope slides
Collection Instructions:Required supplies: Fixative (spray or vial of 95% ETOH), collection spatula, frosted slides and shipping container. Label the slides with the patient's first and last name, date of birth, and specimen source in pencil on the frosted end and place in a container filled with 95% ethyl alcohol so the slides are completely covered. Gently scrape the area of abnormality. If the abnormality is a vesicle, remove the covering and scrape both at the base of the vesicle and around the rim. Remove one of the slides from the fixative. Quickly and evenly smear the collected material on one of the slides. Immediately re-immerse the slide in fixative. Repeat the process with the second slide, if necessary, for better diagnostic yield. Repeat the process for additional areas if necessary. After collection, leave the slides in the 95% alcohol for 10 minutes and then air dry. Submit the specimen and the completed test request form to the Cytology Laboratory.

Processing and Shipping

Specimen Processing:Send smears to Cytology through the pathology department at UMMC Riverside, FSH, FRH, FLHS, FNMC, FRWMC.
Test Performed at or Referral Lab Cytology  (UMMC-East Bank, Fairview Ridges - FRH, Fairview Southdale - FSH, UMMC/UMMCH-West Bank)


Use:Detection and characterization of inflammatory infection processes of the skin, especially herpetic infection.

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