Ribosomal P Protein Antibody, IgG

Sunquest Code:RIBIGG  
Epic Code:LAB6337Epic Name:Ribosomal P Protein Antibody, IgG
Synonyms:rRNP; RNA (Ribonucleo protein) Autoantibodies
Methodology:Multiplex flow immunoassay
Turnaround Time:Performed Mon-Fri; results reported the same day.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Lipemic samples.

Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Reference Range:



Less than 1.0 AI


1.0 AI or greater

Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.



Use:Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than five fold during and before active phases of psychosis.

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