Ribosomal P Protein Antibody, IgG


Sunquest Code:RIBIGG  
Epic Code:LAB6337Epic Name:Ribosomal P Protein Antibody, IgG
Synonyms:rRNP; RNA (Ribonucleo protein) Autoantibodies
Methodology:Multiplex flow immunoassay
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Performed Mon-Fri; results reported the same day.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Lipemic samples.


Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Interpretive

Reference Range:

 

Negative

Less than 1.0 AI

Positive

1.0 AI or greater

Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.

 

 

Use:Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than five fold during and before active phases of psychosis.


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