Cyclic Citrullinated Peptide Antibody, IgG


Sunquest Code:CCPIGG  
Epic Code:LAB6604Epic Name:Cyclic Citrullinated Peptide IgG
Synonyms:Anti-CCP; CCP Antibody
Methodology:FEIA (by ImmunoCAP)
Turnaround Time:Test is performed 1-2 times per week; results are reported the same day.


Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Hemolyzed, lipemic or microbially contaminated specimens. Samples not separated from cells within 2 hours of collection.


Processing and Shipping

Specimen Processing:Within 2 hours centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Endocrine  (UMMC-East Bank)


Interpretive

Reference Range:

Less than 7 Units/mL

Negative

7-10  Units/mL

Equivocal

Greater than 10 Units

Positive

 

Approximately 70% of patients with RA are positive for CCP, while only 5% of random blood donors and disease controls are positive. The diagnostic value of antibodies to CCP in juvenile rheumatoid arthritis patients has not been determined.

 



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