Mycophenolic Acid Area Under the Curve


Sunquest Code:MPAUC  
Epic Code:LAB3136Epic Name:Mycophenolic Acid AUC
Synonyms:MMF; MPA, Area Under the Curve (AUC)
Methodology:Liquid chromatography/tandem mass spectrometry
CPT Code:80180
Turnaround Time:Performed twice a week; results are reported the next day.
Special Instructions:Collect drug levels at baseline, 2 hours, 3 hours and 4 hours post dose. Order as individual MYPA levels and send to laboratory immediately following collection. Only order one MPAUC (area under the curve) calculation per patient.


Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:1 mL
Collection Instructions:Collect levels at baseline, 2 hours, 3 hours and 4 hours post dose.


Processing and Shipping

Specimen Processing:Separate from cells ASAP. Centrifuge and aliquot 1 mL, 0.4 mL minimum. Store in freezer. Whole blood or plasma samples are stable for 4 hours at room temperature, or for 8 hours if refrigerated.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Drug Analysis  (UMMC-East Bank)


Interpretive

Therapeutic Range:30-60 mg*h/L
Use:Pharmacokinetics of mycophenolic acid.


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