Lutropin, Serum


Sunquest Code:LH  
Epic Code:LAB87Epic Name:Lutropin
Synonyms:Interstitial Cell Stimulating Hormone; Luteinizing Hormone, LH
Methodology:Chemiluminescence
CPT Code:83002
Turnaround Time:Performed and reported 24 hours/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (lithium heparin) on ICE, Green (sodium heparin, no gel), Green (sodium heparin, no gel) on ICE, Purple (EDTA), Red (no gel))
Contraindications:Large doses of biotin (10 mg or more per day) may cause clinically significant interference in luteinizing hormone levels. If interference is suspected, it is strongly recommended that biotin is discontinued for at least one week prior to retesting.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Test Performed at or Referral Lab Chemistry  (UMMC-East Bank, Grand Itasca GICH)


Interpretive

Reference Range:
Male (IU/L)
1-15 d Not established
16 d- 10 y 0.3-2.8
11 y 0.3-1.8
12 y 0.3-4.0
13 y 0.3-6.0
14 y 0.5-7.9
15-16 y 0.5-10.8
17 y 0.9-5.9
18-70 y 1.5-9.3
71 y & older 3.1-34.6
  Female (IU/L)
1-15 d Not established
16 d- 6 y 0.3-1.9
7-8 y 3.0 or less
9-10 y 4.0 or less
11 y 6.5 or less
12 y 0.4-9.9
13 y 0.3-5.4
14 y 0.5-31.2
15 y 0.5-20.7
16 y 0.4-29.4
17 y 1.6-12.4
Pre-Menopausal 18 y & older
Follicular phase 1.9-12.5
Midcycle peak 8.7-76.3
Luteal phase 0.5-16.9
Posmenopausal 15.9-54.0
 
Tanner Stages* Males (IU/L) Females (IU/L)
Stage I 0.3-2.7 2.0 or less
Stage II 0.3-5.1 6.5 or less
Stage III 0.3-6.9 0.3-17.2
Stage IV 0.5-5.3 0.5-26.3
Stage V 0.8-11.8 0.6-13.7
  *Puberty onset occurs for boys at a median age of 11.5 (Ɨƃ2) years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner Stage V (adult) should be reached by age 18.   *Puberty onset (transition from Tanner Stage I to Tanner Stage II) occurs for girls at a median age of 10.5 (Ɨƃ2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner Stage V (adult) should be reached by age 18.  
GICH:
Female  
   Mid-Follicular Phase 2.12-10.89
   Mid-Cycle Peak 19.18-103.03
   Mid-Luteal Phase 1.20-12.86
   Postmenopausal 10.87-58.64
Male 10.87-58.64
 
Use:Evaluation of ovarian function and evaluation of infertility in a male partner.
   


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