Kappa/Lambda Quantitative Free Light Chains and Ratio


Sunquest Code:FLCS  
Epic Code:LAB4353Epic Name:KAPPA AND LAMBDA LIGHT CHAIN
Synonyms:Quantitative Kappa Light Chains; Quantitative Lamda Light Chains; Immunoglobulin Free Light Chains; Kappa FLC; Lambda FLC; Serum Free Light Chains; Free Light Chains Ratio
Methodology:Rate turbidimetry
CPT Code:83883 x2, 83883
Turnaround Time:Performed Mon, Wed, Fri. Results are reported within 1-3 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Plasma specimens.


Processing and Shipping

Specimen Processing:Centrifuge ASAP and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Endocrine  (UMMC-East Bank)


Interpretive

Reference Range:

Lambda Quantitative Free Light Chains, Serum

0.57-2.63 mg/dL

Kappa Quantitative Free Light Chains, Serum

0.33-1.94 mg/dL

Kappa/Lambda Free Light Chain Ratio, Serum

0.26-1.65

 

 

Use:This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.


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