Kappa/Lambda Free Light Chains Quantitative


Sunquest Code:FLCS  
Epic Code:LAB4353Epic Name:Kappa/Lambda Free Light Chains
Synonyms:Quantitative Kappa Light Chains; Quantitative Lamda Light Chains; Immunoglobulin Free Light Chains; Kappa FLC; Lambda FLC; Serum Free Light Chains; Free Light Chains Ratio
Methodology:Immunoturbidimetry
Turnaround Time:Performed Mon, Wed, Fri; results are reported within 1-3 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Plasma specimens. Hemolysis.


Processing and Shipping

Specimen Processing:Centrifuge ASAP and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 1 week refrigerated; 2 weeks frozen.
Test Performed at or Referral Lab Endocrine  (UMMC-East Bank)


Interpretive

Reference Range:

Lambda Quantitative Free Light Chains, Serum

0.57-2.63 mg/dL

Kappa Quantitative Free Light Chains, Serum

0.33-1.94 mg/dL

Kappa/Lambda Free Light Chain Ratio, Serum

0.26-1.65

 

 

Use:Aids in the diagnosis and mnitoring of multiple myeloma, lymphoytic neoplasms, Waldenstrom's macroglobulinemia, AL amyloidosis, light chain deposition disease and connective tissue diseases such as systemic lupus erythematosus (SLE) in conjunction with other laboratory and clinical findings.


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