Neutrophil Adhesion Markers


Sunquest Code:NEUTAD  
Epic Code:LAB6135Epic Name:Neutrophil Adhesion Markers
Synonyms:LAD
Methodology:Flow cytometry
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to reference laboratory Mon-Thur before 1300; results are reported within 7 days.
Special Instructions:A signed informed consent in the patient's medical record is required. The completed requisition form should not be sent to the laboratory. Samples must be received at testing site within 24 hours of collection. A completed requisition form must be sent with each sample. See Associated Links for both forms. Please call 513-636-4685 with courier and sample tracking number.
Associated Links:

Genetic Testing Consent Form, Cincinnati Children's Hospital Requisition Form



Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:1 mL
Collection Instructions:Specimens must be collected after 10:00 am and sent to the reference laboratory by 1400 to be received within 24 hours of collection.
Causes for Rejection:Specimens greater than 24 hours old. Refrigerated or frozen specimens. Clotted, hemolyzed or centrifuged specimens.


Processing and Shipping

Specimen Processing:Whole blood. Do not process.
Shipping Instructions:Ship sample same day at room temperature. Must arrive at testing site within 24 hours of collection and before 17:00 on Fridays.
Test Performed at or Referral Lab Lab Sendouts  (Cincinnati Children's Hospital Medical Center)
Referral Lab number:2902070


Interpretive

Reference Range:By report
Use:

CD11b/CD18 and its endothelial cell ligands including intracellular adhesion molecule-1 (ICAM-1, CD54) are necessary for firm neutrophil adherence and transendothelial migration. Leukocyte adhesion deficiency syndrome type 1 (LAD-1) results from a congenital deficiency of the leukocyte b2 intergrin receptor complex CD11/CD18 on the cell surface.

 

 



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