Free Kappa and Lambda Light Chains, Quantitative, Urine

Sunquest Code:KLLTCH  
Epic Code:LAB4336Epic Name:Free Kappa and Lambda Light Chains, Urine
Synonyms:Kappa, Lamda Light Chains, Bence Jones Proteins
Methodology:Immunnofixation electrophoresis, nephelometry
CPT Code:83883 x2, 84156, 86335
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-5 days.
Associated Links:

Urine Collection Procedure

Collection Instructions

Specimen:Urine, 24 hour collection or random
Optimal Volume:Submit entire 24 collection; analysis requires 4 mL minimum
Collection Instructions:Refrigerate during collection.
Causes for Rejection:Frozen specimens

Processing and Shipping

Specimen Processing:Mix collection well before aliquot is taken. Transfer specimen to two 4 mL aliquots; one 4 mL aliquot minimum. Store in refrigerator. Record total volume and collection time interval on transport tube and test request form.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50618


Reference Range:

Total Protein

10-140 mg/d

Albumin, Urine


Alpha-1 Globulins, Urine

None detected

Alpha-21 Globulins, Urine

None detected

Beta Globulins, Urine

None detected

Gamma, Urine

None detected

Free Urinary Kappa Light Chains

0.14-2.42 mg/dL

Free Urinary Kappa Excretion/Day

By report

Free Urinary Lambda Light Chains

0.02-0.67 mg/dL

Free Urinary Lambda Excretion/Day

By report

Free Urinary Kappa/Lambda Ratio

2.04-10.37 (ratio)

IFE Interpretation

By report



Use:Total urinary protein is determined nephelometrically by adding the albumin and kappa and/or lambda light chains. This value may not agree with the total protein as determined by chemical methods, which characteristically underestimate urinary light chains.

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