D-Dimer, Fairview Range Hospital and Clinics, and Grand Itasca only


Sunquest Code:DIMER  
Epic Code:LAB5894Epic Name:D Dimer (FV Range)
Synonyms:Fibrin D-Dimer; D Dimer
Methodology:Immunoassay
CPT Code:85379
Turnaround Time:Performed 24 hours/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Collection Instructions:For correct anticoagulant to blood ratio, place 2.7 mL blood in 3 mL tube, or 1.8 mL in 2 mL tube. If the patient's hematocrit is greater than 55%, contact laboratory to obtain a special tube.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.5 mL minimum. Freeze if testing cannot be completed within 4 hours.
Shipping Instructions:Ship at room temperature to arrive for testing within 4 hours. Freeze if testing will be delayed beyond 4 hours.
Test Performed at or Referral Lab Coagulation  (Fairview Range - FRMC, Grand Itasca GICH)


Interpretive

Reference Range:0-300 ng/mL D-DU
GICH: 0-230 ng/mL
Use:

D-Dimer is a specific marker of the breakdown of a cross-linked fibrin clot (i.e., fibrinolysis) and an indirect marker of clot formation. Elevated levels of D-Dimer are present in a wide variety of disorders known to be associated with activation of coagulation:

·          Pre-DIC conditions and DIC

·          Sickle cell disease

·          Pregnancy, higher if complicated

·          Renal diseases

·          Arterial thrombosis

·          Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE)

 



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