AFP Tumor Marker


Sunquest Code:FETO  
Epic Code:LAB559Epic Name:AFP Tumor Marker
Synonyms:Alpha Fetoprotein; Alphafetoprotein; Nonpregnant Alpha Fetoprotein
Methodology:Chemiluminescent immunoassay
CPT Code:82105
Turnaround Time:Performed and reported 24 hours/day.
Special Instructions:This test is used as a tumor marker, not for neural tube defect screening.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Gross hemolysis


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Test Performed at or Referral Lab Chemistry  (UMMC-East Bank)


Interpretive

Reference Range:1 year and up <8.1 ug/L. Reference values for adult non-pregnant female only, fetal production of AFP elevates values in pregnant women. Ranges for newborns are not available, but concentrations over 100,000 ug/L have been reported in normal newborns. Values rapidly decline to <100 ug/L by 5 months and reach adult levels by 1 year. The ADVIA Centaur AFP method is used. Results obtained with different assay methods or kits cannot be used interchangeably.
Use:Aids in the differential diagnosis and therapeutic monitoring of germinal neoplasms of the testis, ovary, retroperitoneum, mediastinum, and heptocellular carcinoma. Seminomas do not produce AFP.


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