Insulin Like Growth Factor 1 (IGF1), Pediatric


Sunquest Code:IGF1Q  
Epic Code:LAB6350Epic Name:Insulin Like Growth Factor 1 (IGF-1) Pediatric
Synonyms:IGF-1, LC/MC; Insulin-Like Growth Factor
Methodology:Liquid chromatography/Mass spectrometry (LC/MS)
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 2-5 days.
Compliance:

This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. Performance characteristics refer to the analytical performance of this test.



Collection Instructions

Specimen:Blood
Optimal Volume:1.5 mL
Minimum\Peds Volume:0.8 mL
Container:See Collection Instructions (West Bank: Special red no gel BD tube that has green "IGF1Q to Quest" sticker, obtained from the lab, Red (no gel))
Collection Instructions:UMMC-West Bank Only: Collect in the special red, no gel tubes labeled with the green "IGF1A to Quest" stickers.
Causes for Rejection:Room temperature specimens, grossly hemolyzed, lipemic or icteric specimens. Specimens received in a glass tube.


Processing and Shipping

Specimen Processing:Allow blood to clot for 10-15 minutes at room temperature. Centrifuge and aliquot 0.5 mL, 0.3 mL minimum. Store in frozen.
Shipping Instructions:Ship frozen.
Test Performed at or Referral Lab Lab Sendouts  (Quest)
Referral Lab number:16293


Interpretive

Reference Range:By report.
Use:Insulin-like growth factor I (IGF-I or somatomedin C), a protein involved in stimulating somatic growth, is regulated principally by growth hormone (GH) and nutritional intake. IGF-I is transported in serum by several proteins; this helps maintain relatively high IGF-I plasma levels and minimizes fluctuations in serum IGF-I concentrations. Measuring IGF-I is useful in several growth-related disorders. Dwarfism caused by deficiency of growth hormone (hypopituitarism) results in decreased serum levels of IGF-I, while acromegaly (growth hormone excess) results in elevated levels of IGF-I. IGF-I measurements are also helpful in assessing nutritional status; levels are reduced in undernutrition and restored with a proper diet.


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