Cytochrome P450 2C19 Genotype - LG4981


Sunquest Code:MMMISC  
Epic Code:LA4909Epic Name:Send Outs Misc Test
Methodology:Polymerase chain reaction (PCR)/with Allelic Discrimination
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 1-5 days.
Special Instructions:Transfusions will interfere with testing for up to 4-6 weeks. DNA obtained from white cells may not provide useful information for patients who received a recent transfusion of blood that was not leukocyte-reduced. Wait 4-6 weeks until transfused cells have left the patient's circulation before drawing the patient's blood specimen for genotype testing. A signed informed consent in the patient's medical record is required; the consent form should not be sent to the laboratory. See Associated Links.
Compliance:

This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared by the U.S. Food and Drug Administration.

Associated Links:

Genetic Testing Consent Form



Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:0.4 mL
Container:Purple (EDTA)


Processing and Shipping

Specimen Processing:Whole blood. Do not process. Store at room temperature.
Shipping Instructions:Ship in original container at room temperature.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:2C19V


Interpretive

Reference Range:By report.
Use:Identifying patients who may be at risk for altered metabolism of drugs that are modified by CYP2C19.
Predicting anticoagulation response to Clopidogrel.


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