CD4 T-Cell Recent Thymic Emigrants (RTE)


Sunquest Code:CD4RTE  
Epic Code:LAB7011Epic Name:CD4 T-Cell Recent Thymic Emigrants
Synonyms:CD4 RTE, Flow Cytometry; T cell
Methodology:Flow cytometry
CPT Code:86356 x3
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-4 days
Special Instructions:Specimen must be analyzed within 72 hours of collection. *Ordering physician name and phone number are required.
Compliance:

Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.



Collection Instructions

Specimen:Whole blood
Optimal Volume:4 mL
Minimum\Peds Volume:0.5 mL
Container:Purple (EDTA) (Green (sodium heparin, no gel))
Causes for Rejection:Cord blood. Specimens older than 72 hours. Clotted or hemolyzed specimens. Frozen specimens.


Processing and Shipping

Specimen Processing:Whole blood. Store at room temperature or refrigerated.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010179


Interpretive

Reference Range:

% CD4+CD31+CD45RA+(RTEs)

Age

Reference Interval

1 w – 2 mo

50-100% of CD4+

2-5 mo

64-94% of CD4+

5-9 mo

65-90% of CD4+

9-15 mo

61-93% of CD4+

15-24 mo

10-100% of CD4+

2-5 y

37-100% of CD4+

5-10 y

51-81% of CD4+

10-16 y

31-81% of CD4+

>16 years

6-51% of CD4+

 

Abs CD4+CD31+CD45RA+(RTEs)

Age

Reference Interval

1 w – 2 mo

1000-4900 cells/µL

2-5 mo

1400-5200 cells/µL

5-9 mo

800-6200 cells/µL

9-15 mo

900-5800 cells/µL

15-24 mo

170-7400 cells/µL

2-5 y

190-2600 cells/µL

5-10 y

200-1700 cells/µL +

10-16 y

150-1500 cells/µL

>16 years

51-609 cells/µL

 

 

Use:Assess thymic function in suspected severe combined immunodeficiency (SCID), DiGeorge syndrome and other T-cell immune deficiency disorders. Evaluate immune reconstitution during highly active antiviral therapy (HAART) in HIC patients and post-chemotherapy and hematopoietic cell transplant.


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