CD4 Plus T-Cell Recent Thymic Emigrants (RTE)

Sunquest Code:CD4RTE  
Epic Code:LAB7011Epic Name:CD4 T-Cell Recent Thymic Emigrants
Synonyms:T Cell Recent Thymic; CD4 RTE, Flow Cytometry; T cell
Methodology:Flow cytometry
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-4 days
Special Instructions:Specimen must be analyzed within 72 hours of collection. *Ordering physician name and phone number are required.

Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Collection Instructions

Specimen:Whole blood
Optimal Volume:4 mL
Minimum\Peds Volume:0.5 mL
Container:Purple (EDTA) (Green (sodium heparin, no gel))
Causes for Rejection:Cord blood. Specimens older than 72 hours. Clotted or hemolyzed specimens. Frozen specimens.

Processing and Shipping

Specimen Processing:Whole blood. Store at room temperature or refrigerated.
Shipping Instructions:Ship at refrigerated temperature.
Stability:72 hours at room temperature or refrigerated.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010179


Reference Range:
% CD4+CD31+CD45RA+(RTEs)
Age Reference Interval
1 w - 2 mo 50-100% of CD4+
2 - 5 mo 64-94% of CD4+
5 - 9 mo 65-90% of CD4+
9 - 15 mo 61-93% of CD4+
15 - 24 mo 40-100% of CD4+
2 - 5 y 37-100% of CD4+
5 - 10 y 41-81% of CD4+
10-16 y 31-81% of CD4+
>16 y 50-100% of CD4+
  Abs CD4+CD31+CD45RA+(RTEs)
Age Reference Interval
1 w - 2 mo 1000-4900 cells/µL
2 - 5 mo 1400-5200 cells/µL
5 - 9 mo 800-6200 cells/µL
9 - 15 mo 900-5800 cells/µL
15 - 24 mo 170-7400 cells/µL
2 - 5 y 190-2600 cells/µL
5 - 10 y 200-1700 cells/µL
10-16 y 150-1500 cells/µL
>16 y 51-609 cells/µL
Use:Assess thymic function in suspected severe combined immunodeficiency (SCID), DiGeorge syndrome and other T-cell immune deficiency disorders. Evaluate immune reconstitution during highly active antiviral therapy (HAART) in HIC patients and post-chemotherapy and hematopoietic cell transplant.

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