Serotnnin Transporter Genotype (HTT or SLC6A4)

Sunquest Code:HTT  
Epic Code:LAB6347Epic Name:Serotnnin Transporter Genotype HTT or SLC6A4
Methodology:Polymerase chain reaction (PCR) followed by sizing analysis
CPT Code:81479
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 1-4 days.
Special Instructions:Bone marrow transplants will interfere with testing. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700 for instructions. Transfusions will interfere with testing for up to 4 to 6 weeks. DNA obtained from white cells may not provide useful information for patients who received a recent transfusion of blood that was not leukocyte-reduced. Wait 4 to 6 weeks until transfused cells have left the patient's circulation before drawing the patient's blood specimen for genotype testing. A signed informed consent in the patient's medical record is required; the consent form should not be sent to the laboratory. See Associated Links.

This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared by the U.S. Food and Drug Administration.

Associated Links:

Genetic Testing Consent Form

Collection Instructions

Optimal Volume:3 mL
Minimum\Peds Volume:0.3 mL

Processing and Shipping

Specimen Processing:Whole blood. Do not process. Store at room temperature (preferred) or refrigerated temperature.
Shipping Instructions:Ship at room temperature (preferred) or refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:HTT


Use:Identifying patients who have diminished amounts of the serotonin transporter and, hence, an altered response to SSRI therapeutics.

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