Carnitine, Plasma


Sunquest Code:CARNPM  
Epic Code:LAB6781Epic Name:Carnitine, Plasma
Methodology:Flow injection analysis/Tandem mass spectrometry (FIA-MS/MS)
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 2-5 days.
Special Instructions:Assay must have its own separate frozen tube.
Compliance:

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.



Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.6 mL
Container:Green (sodium heparin, no gel) on ICE (Purple (EDTA) on ICE)
Causes for Rejection:Gross hemolysis or lipemia. Collected in a gel tube.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store frozen (preferred).
Shipping Instructions:Ship on dry ice.
Stability:Stability: 7 days - room temperature; 21 days - refrigerated; 60 days - frozen.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:CARN


Interpretive

Reference Range:
Age Total Carnitine (TC)
nmol/mL
Free Carnitine (FC)
nmol/mL

Acyclcarnitine (AC)
nmol/mL

AF/FC Ratio
nmol/mL

< or = 1 d 23-68 12-36 7-37 0.4-1.7
2-7 d 17-41 10-21 3-24 0.2-1.4
8-31 d 19-59 12-46 4-15 0.1-0.7
32 d - 12 mo 38-68 27-49 7-19 0.2-0.5
13 mo - 6 y 35-84 24-63 4-28 0.1-0.8
 
Use:Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias, fatty acid oxidation disorders, and primary carnitine deficiency.


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