ADAMTS13 Activity with Reflex to Inhibitor and Antibody


Sunquest Code:ADAMEV  
Epic Code:LAB6839Epic Name:ADAMTS13 Activity W Reflex to Inhib ABY
Synonyms:ADAMTS Evaluation; VWF Cleaving Protease
Methodology:See individual test codes
CPT Code:----------CPTCODES HERE----------
Test Includes:ADAMTS13 activity with reflex to inhibitor and antibody is a reflexive testing algorithm. ADAMTS13 Activity is always performed. If activity is less than or equal to 30%, the inhibitor assay is performed. If the inhibitor is less than or equal to 0.7 Inhibitor Units, testing for ADAMTS13 is performed.
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 7 days.
Special Instructions:Send platelet-poor plasma for testing. See Specimen Collection and Processing for Special Coagulation Specimens Associated Link.
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube
Causes for Rejection:Over-filled or under-filled tubes. Hemolyzed or clotted specimens.


Processing and Shipping

Specimen Processing:See Special Coagulation processing instructions. Aliquot 1.5 mL, 1.2 mL minimum. Store in freezer.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (Blood Center of Wisconsin)
Referral Lab number:1295


Interpretive

Reference Range:

ADAMTS13 Activity

Greater than or equal to 67%

ADAMTS13 Inhibitor

Less than or equal to 0.4 Inhibitor Units

ADAMTS13 Antibody

Less than or equal to 18 Arbitrary Units

 

 

Use:Diagnosis of congenital or idiopathic thrombotic thrombocytopenic purpura (TTP).


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