Protein C, Total Antigen


Sunquest Code:PRCAGN  
Epic Code:LAB6891Epic Name:Protein C Antigen
Methodology:Immunoassay
CPT Code:85302
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-2 days.
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:Two 2.7 mL (in 3 mL tube) - filled to fill line on the tube
Minimum\Peds Volume:One 2.7 mL (in 3 mL tube) - ffilled to fill line on the tube
Causes for Rejection:Serum, EDTA plasma, clotted or hemolyzed specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 1 mL minimum. Freeze immediately.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:30111


Interpretive

Reference Range:

1-4 d

17-35%

5-29 d

20-64%

30-89 d

21-65%

90-179 d

28-80%

180-364 d

37-81%

1-5 y

40-92%

6-10 y

45-93%

11 y and older

63-153%

 

 

Limitations:Patients on warfarin may have decreased Protein C values. Patients should be off Warfarin therapy for two weeks for accurate measurement of Protein C.
Use:Aids in diagnosis of congenital deficiencies characterized by recurrent venous thrombosis. Acquired deficiencies associated wit Protein C include: oral anticoagulant therapy, liver disease, vitamin K deficiency. Malignancy, consumptive DIC, surgery, trauma, antibodies to Protein C and hepatic immaturity of the newborn.


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