Anti Ku Antibody - LG5393


Sunquest Code:LSMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Methodology:Enzyme linked immunosorbent assay (ELISA).
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 16 days.
Compliance:

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.



Collection Instructions

Specimen:Blood
Optimal Volume:2.2 mL
Minimum\Peds Volume:1.2 mL   Does not permit repeat analysis
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types.


Processing and Shipping

Specimen Processing:Within one hour of collection centrifuge and aliquot 1 mL; 0.5 mL minimum.   Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:7 days room temperature; 14 days refrigerated; 60 days frozen.
Test Performed at or Referral Lab Lab Sendouts  (LabCorp via ARUP)
Referral Lab number:520030


Interpretive

Reference Range:Negative
Use:Anti-Ku antibodies are found in about 20% of IIM; associated with overlap syndromes such as PM/SSc (most common), SLE/PM and other autoimmune disorders such as PM, SS, SSc, SLE, UCTD, MCTD, RA; common clinical features include arthralgias/arthritis, myositis, Raynaud's, esophageal dysmotility and ILD.


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